Gross-to-Net Consulting Services

Transform Revenue Complexity into a Strategic Advantage 

With complex pricing structures, multiple market segments, and various discounts, your ability to forecast net revenue accurately is not just a finance function — it’s your competitive advantage. 

Argano helps pharmaceutical, biotech, and medical device companies navigate the intricacies of commercial rebates, chargebacks, government discounts, and returns — and move more quickly to profitability. 

Argano’s GTN edge

We start with the business problem, not the platform. We understand your revenue operations, your contracting complexity, and your margins — then align the right technology to protect them. The result is high-performance revenue operations: better decisions, stronger margins, and measurable impacts to your bottom line. 

Forecast with confidence

Model utilization and discounting by market segment, starting at the contract level — and improve your ability to predict net revenue in future periods, not just explain the last one.

Optimize accruals

Quantitatively assess the discounts flowing through each contract component and channel, enabling improved accrual accuracy, better informed reserves, and immediate bottom-line impact. 

Protect your margins

Identify and close the gaps where revenue disappears — miscalculated rebates, delayed chargeback processing, uncollected wholesaler fees — before they compound across quarters. 

Speed compliance

Ensure calculation methodologies align strictly with statutory guidelines and government pricing programs, including Medicaid Rebates, Medicare Part D coverage gaps, and the 340B Drug Pricing Program — with audit-defensible precision from day one. 

Automate and optimize

Move beyond fragmented spreadsheets and legacy software. We integrate and optimize platforms to automate calculations, reduce manual errors, and deliver value 6–12 months faster than traditional system integrators. 

Align the enterprise

GTN touches finance, commercial operations, legal, and more. Argano bridges the gaps between departments — removing silos and aligning workflows, data, and assumptions around a single, connected view of revenue. 

GTN expertise across pharma and other critical markets 

Argano’s life sciences practice drives high-performance operations across pharmaceuticals, biotechnology, medical devices, and more. Our GTN modeling capabilities serve organizations from emerging biotechs to large global pharma. 

Pharmaceuticals

Established portfolios with mature commercial models. Complex government pricing programs (340B, Medicaid Best Price, Medicare Part D), chargebacks, and multi-tier rebate structures across branded and generic products.

Biotechnology

The same GTN waterfall as pharma — rebates, chargebacks, 340B, Best Price — but often with less mature systems and greater leakage risk. We help biotechs build GTN capability from the ground up, including investor-grade net revenue diligence.

Medical Devices

GPO and IDN contracts, distributor layers, and volume attainment rebates obscure true net price. We bring visibility to multi-contract pricing, distribution fees, and revenue leakage across complex medtech channels.

Unified GTN performance management

True GTN management requires more than static calculations — it demands a dynamic operational engine. 

Our EPM solution bridges the gap between GTN complexity and enterprise-wide financial planning, giving you the platform you need to forecast with confidence, optimize accruals, and turn revenue data into strategic clarity. Built on proven platforms like Anaplan and Oracle EPM, we configure your GTN logic for the unique nuances of pharma, biotech, and medtech revenue operations. 

  • Connected GTN Model — Translate complex GTN mechanics into a single, connected model that links contracts, channels, and market segments — replacing top-down percentage estimates with bottom-up, driver-based forecasting. 

  • Real-Time Visibility — Move from end-of-month spreadsheet reconciliation to real-time EPM dashboards that track GTN accrual status, discount utilization, and net revenue trends as they happen. 

  • Scenario Planning — Model the financial impact of price changes, rebate adjustments, and contract renegotiations before they happen — giving leadership quantified confidence in their GTN projections. 

  • Scalable Architecture — From emerging biotech to global pharma, leverage an EPM platform that scales with your portfolio, data volumes, and GTN contracting complexity — without the rebuilds that spreadsheets demand. 

From biotech startups to Fortune 100 pharma companies, Argano provides what’s needed to help clients forecast net revenue with confidence, optimize accruals, and protect margins with audit-defensible precision. Let’s assess your GTN readiness together. 

Assess your GTN readiness